Thermo Fisher Scientific TIMM8A Monoclonal Antibody (OTI5C8), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

TIMM8A is a mitochondrial intermembrane chaperone involved in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.
It facilitates transfer of beta-barrel precursors from the TOM complex to the SAM complex of the outer membrane, preventing aggregation of hydrophobic precursors.
The TIMM8-TIMM13 complex mediates import of proteins such as TIMM23, SLC25A12/ARALAR1, and SLC25A13/ARALAR2.
Proper TIMM8A function is likely essential for normal neurological development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.