Thermo Fisher Scientific SHROOM3 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SHROOM3

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647290

Product Specific Information

Immunogen sequence: EEGTRKRVSL PQWPPPSRAK WAHAAREDSL PEESSAPDFA NLKHYQKQQS LPSLCSTSDP DTPLGAPSTP GRISLRISES VLRDSPPPHE DYEDEVF

Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.

Target Information

SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM3 is an actin-binding protein is a regulator of the microtubule cytoskeleton during epithelial morphogenesis and is sufficient and necessary to induce a redistribution of the microtubule regulator gamma-tubulin. It is necessary for both apiscobasal cell elongation and apical constriction in the neural epithelium. SHROOM3 has also been shown to be essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription relying on the Pitx1 transcription factor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.