Thermo Fisher Scientific SHROOM3 Polyclonal Antibody
Rabbit polyclonal antibody against human SHROOM3 recombinant protein. Liquid form, unconjugated, 0.1 mg/mL concentration. Suitable for research use in studies of epithelial morphogenesis and cytoskeletal regulation. Store at 4°C short term or -20°C lon...
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Thermo Fisher Scientific SHROOM3 Polyclonal Antibody
제품 사양
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SHROOM3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647290 |
Product Specific Information
Immunogen sequence:
EEGTRKRVSL PQWPPPSRAK WAHAAREDSL PEESSAPDFA NLKHYQKQQS LPSLCSTSDP DTPLGAPSTP GRISLRISES VLRDSPPPHE DYEDEVF
Highest antigen sequence identity to the following orthologs:
- Mouse: 66%
- Rat: 67%
Target Information
SHROOM family members play diverse roles in the development of the nervous system and other tissues.
SHROOM3 is an actin-binding protein that regulates the microtubule cytoskeleton during epithelial morphogenesis and induces redistribution of the microtubule regulator gamma-tubulin.
It is required for apicobasal cell elongation and apical constriction in the neural epithelium.
SHROOM3 is also essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription dependent on the Pitx1 transcription factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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