Thermo Fisher Scientific MBTPS1 Monoclonal Antibody (2F10E12)
MBTPS1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(2F10E12)입니다. Western blot, Flow cytometry, ELISA에 사용 가능하며, 인간 시료에 반응합니다. Protein G로 정제된 액상 형태로, -20°C 이하에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F10E12 |
| Immunogen | Recombinant Human Membrane-bound transcription factor site-1 protease protein (187–400aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.25 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091051 |
Target Information
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway.
The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired.
It encodes a type 1 membrane-bound protease that is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues.
Mutations in this gene may be associated with lysosomal dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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