Thermo Fisher Scientific CCL5 (RANTES) Recombinant Rabbit Monoclonal Antibody (JM03-45)
Human 및 Mouse 반응성을 가진 recombinant rabbit monoclonal antibody로, Western blot, IHC, ICC/IF에 사용 가능. HEK293 세포에서 발현되었으며 Protein A로 정제됨. 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용.
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Thermo Fisher Scientific CCL5 (RANTES) Recombinant Rabbit Monoclonal Antibody (JM03-45)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM03-45 |
| Immunogen | Recombinant protein within human RANTES aa 1–91 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2931462 |
Target Information
CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.
CCL5 functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It induces histamine release from basophils and activates eosinophils.
This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells, acting as a natural ligand for CCR5 and suppressing in vitro replication of R5 strains of HIV-1.
Alternative splicing results in multiple transcript variants encoding different isoforms.
Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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