Thermo Fisher Scientific BACE2 B Polyclonal Antibody, Biotin
인간 및 영장류 시료에 반응하는 BACE2 B 폴리클로날 항체로, Biotin 결합형입니다. Western blot, ELISA, IP 등에 사용 가능하며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도 Affinity chromatography 정제 및 안정적 보관이 가능합니다.
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- BACE2B-BIOTIN
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 350–396 on human BACE2B protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It can also cleave APP between residues 671 and 672. Additionally, it is responsible for the proteolytic processing of CLTRN in pancreatic beta cells (PubMed:21907142).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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