Thermo Fisher Scientific BACE2 B Polyclonal Antibody, FITC
BACE2 B 단백질을 인식하는 FITC 결합 토끼 다클론 항체로, Western blot, ELISA, IP에 적합. 인간 및 비인간 영장류에 반응하며, 형광 분석용으로 최적화됨. -20°C 암소 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 350–396 on human BACE2B protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It can also cleave APP between residues 671 and 672. Additionally, responsible for the proteolytic processing of CLTRN in pancreatic beta cells (PubMed:21907142).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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