Thermo Fisher Scientific VAV1 Monoclonal Antibody (ZV003)
VAV1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체 ZV003. Western blot, ICC/IF, ELISA 등 다양한 응용 가능. 인간 및 조류 시료에서 검증됨. 비결합형 액상 포맷으로 제공되며 -20°C에서 보관.
- 카탈로그번호
- 392050
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Chicken, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZV003 |
| Immunogen | Synthetic peptide derived from an internal region of the human, mouse and rat Vav1 proteins |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2533400 |
Target Information
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open-angle glaucoma. It interacts with adenovirus E3-14.7K protein and may utilize TNF-α or Fas-ligand pathways to mediate apoptosis, inflammation, or vasoconstriction. Optineurin may also function in cellular morphogenesis, membrane trafficking, vesicle trafficking, and transcription activation through its interactions with RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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