Thermo Fisher Scientific BCL2L12 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

BCL2L12 (NP_001035758.1, 1 a.a. approximately 333 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BCL2L12,uniProtId:Q9HB09-1,ncbiNodeId:9606,antigenRange:1-334,antigenLength:334,antigenImageFileName:H00083596-B01P_BCL2L12_Q9HB09-1_House_mouse.svg,antigenImageFileNamePDP:H00083596-B01P_BCL2L12_Q9HB09-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MGRPAGLFPP LCPFLGFRPE ACWERHMQIE RAPSVPPFLR WAGYRPGPVR RRGKVELIKF VRVQWRRPQV EWRRRRWGPG PGASMAGSEE LGLREDTLRV LAAFLRRGEA AGSPVPTPPS PAQEEPTDFL SRLRRCLPCS LGRGAAPSES PRPCSLPIRP CYGLEPGPAT PDFYALVAQR LEQLVQEQLK SPPSPELQGP PSTEKEAILR RLVALLEEEA EVINQKLASD PALRSKLVRL SSDSFARLVE LFCSRDDSSR PSRACPGPPP PSPEPLARLA LAMELSRRVA GLGGTLAGLS VEHVHSFTPW IQAHGGWEGI LAVSPVDLNL PLD

Target Information

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.