Thermo Fisher Scientific RBMXL2 Polyclonal Antibody
Human RBMXL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer(40% glycerol 포함)에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RBMXL2. Recombinant protein control fragment (Product # RP-97463) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646407 |
Product Specific Information
- Immunogen sequence: GGRDRDYGDH LSRGSHREPF ESYGEL
- Highest antigen sequence identity to orthologs: Mouse – 62%, Rat – 58%
Target Information
The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport.
While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm.
RBMXL2 contains two RRM domains that bind RNAs and shares similarity with HNRPG and RBMY proteins. It may replace HNRPG function during meiotic prophase or act as a germ cell-specific splicing regulator.
RBMXL2 primarily localizes to the nuclei of meiotic spermatocytes and is a candidate gene for autosomal male infertility.
This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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