Thermo Fisher Scientific CDC6 Monoclonal Antibody (OTI1A4), TrueMAB
Human CDC6 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(P)에서 검증됨. Affinity chromatography로 정제된 액상 형태로 제공. PBS, BSA, glycerol buffer에 보관하며 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A4 |
| Immunogen | Full length human recombinant protein of human CDC6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in the cell nucleus during the G1 phase of the cell cycle but translocates to the cytoplasm at the start of the S phase. The subcellular translocation of this protein during the cell cycle is regulated through its phosphorylation by Cdks. Transcription of this protein is regulated in response to mitogenic signals through transcriptional control mechanisms involving E2F proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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