Thermo Fisher Scientific CDC6 Monoclonal Antibody (OTI7B12), TrueMAB
Thermo Fisher Scientific의 CDC6 단클론 항체(OTI7B12)는 인간 CDC6 단백질을 인식하는 Mouse IgG1 형 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 액상 형태로 공급됩니다. DNA 복제 연구 및 세포 주기 조절 관련 연구에 적합합니다.
- 카탈로그번호
- TA808380
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B12 |
| Immunogen | Full length human recombinant protein of human CDC6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication.
This protein functions as a regulator at the early steps of DNA replication. It localizes in the cell nucleus during the G1 phase, but translocates to the cytoplasm at the start of the S phase.
The subcellular translocation of this protein during the cell cycle is regulated through phosphorylation by Cdks.
Transcription of this protein is regulated in response to mitogenic signals through a transcriptional control mechanism involving E2F proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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