Thermo Fisher Scientific SDHB Polyclonal Antibody
Thermo Fisher Scientific의 SDHB Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 rabbit IgG 항체입니다. Western blot, IHC, ICC/IF 실험에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 미토콘드리아 복합체 II 연구용으로 설계된 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human SDHB recombinant protein (Position: A29–V280) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2747080 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Complex II of the respiratory chain is specifically involved in the oxidation of succinate and carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters that may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene are associated with paragangliomas and pheochromocytoma, supporting a link between mitochondrial dysfunction and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-79965_SDHB_P21912-1_Rabbit.svg, PA5-79965_SDHB_P21912-1_Rabbit_PDP.jpeg)
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