Thermo Fisher Scientific LYL1 Polyclonal Antibody
Rat LYL1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. 합성 펩타이드로부터 제작되어 높은 특이성과 재현성을 보장. PBS 완충액에 보관되며, -20°C에서 냉동 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of rat LYL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691101 |
Product Specific Information
This target displays homology in the following species:
- Mouse: 100%
- Rat: 86%
Target Information
Lyl-1, TAL1, and TAL2 belong to a family of basic helix-loop-helix (bHLH) proteins implicated in T cell acute leukemia.
TAL1 (also known as SCL) is a serine phosphoprotein and transcription factor regulating embryonic hematopoiesis.
TAL2 is involved in T cell acute lymphoblastic leukemia through chromosomal translocation with T cell receptor β genes.
Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein forming heterodimeric complexes with E2α proteins, showing distinct DNA-binding properties in hematolymphoid cells.
Lyl-1 is associated with chromosomal aberrations leading to T cell acute lymphoblastic leukemia (T-ALL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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