Thermo Fisher Scientific HSF2 Polyclonal Antibody
Thermo Fisher Scientific의 HSF2 Polyclonal Antibody는 마우스 HSF2 단백질을 인식하는 고품질 항체입니다. WB에 적합하며 0.2–1.0 µg/mL 농도로 사용됩니다. Rabbit IgG 폴리클로날 항체로, 액상 형태이며 PBS + sucrose buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse HSF2 (UniProt ID: P38533-1, antigen range: 459–508) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689295 |
Product Specific Information
This target displays homology in the following species:
- Human: 86%
- Mouse: 100%
- Rabbit: 86%
- Rat: 100%
Target Information
Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing a group of genes collectively designated heat shock genes. In eukaryotes, this gene expression is regulated primarily at the transcription level. Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation.
HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity, and is translocated to the nucleus.
HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-68770_HSF2_P38533-1_Rabbit.svg)
(이미지: PA5-68770_HSF2_P38533-1_Rabbit_PDP.jpeg)
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