Thermo Fisher Scientific ACSL5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ACSL5 C-terminal region. Validated for WB and IHC applications. Supplied as a liquid, unconjugated form at 0.5 mg/mL. Suitable for research use in lipid metabolism and glioma studies.
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- PA542999
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human ACSL5 (aa 470–519) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576577 |
Product Specific Information
Peptide sequence:
ACNYVKLEDV ADMNYFTVNN EGEVCIKGTN VFKGYLKDPE KTQEALDSDG
Sequence homology:
Cow: 92%
Dog: 93%
Guinea Pig: 86%
Horse: 86%
Human: 100%
Mouse: 100%
Rabbit: 86%
Rat: 100%
Zebrafish: 93%
Target Information
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, thereby playing a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but shows markedly increased levels in malignant gliomas. It functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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