Thermo Fisher Scientific HIP55 Polyclonal Antibody
HIP55 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB와 IHC에 사용 가능. 높은 특이성과 재현성을 제공하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–202 of Human HIP55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.99 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548681 |
Product Specific Information
- Recommended positive control: Raji
- Predicted reactivity: Mouse (95%), Rat (96%), Xenopus laevis (86%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication. The hexameric complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in replication fork formation and recruitment of other DNA replication-related proteins.
The MCM complex consisting of this protein and MCM2, 6, and 7 proteins possesses DNA helicase activity and may act as a DNA unwinding enzyme. Phosphorylation by CDC2 kinase reduces helicase activity and chromatin binding. This gene is mapped on chromosome 8 near PRKDC/DNA-PK, involved in DNA double-strand break repair. Alternatively spliced transcript variants encoding the same protein have been reported.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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