Thermo Fisher Scientific STEAP4 Polyclonal Antibody
인간 STEAP4 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 검증 완료, 2.5 µg/mL 권장 희석. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS와 0.1% sodium azide 포함. STEAP4 관련 암 및 대사 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from N-terminus of human STEAP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551577 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human (100%)
- Gorilla, Monkey, Marmoset (93%)
- Gibbon, Mouse, Bat, Horse (87%)
- Hamster, Elephant, Panda, Rabbit, Pig, Xenopus (80%)
Target Information
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue.
Similar to STEAP2 and STEAP3, STEAP4 promotes both iron and copper reduction.
STEAP4 is highly expressed in placenta, lung, heart, and prostate tissues, and is overexpressed in prostate cancer cells compared to normal prostate cells.
Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting a role in cell proliferation and prostate cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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