Thermo Fisher Scientific PPP1R10 Polyclonal Antibody
PPP1R10 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 면역세포염색에 적합하며, 인간 단백질에 반응. 합성 펩타이드(N-말단 aa146-195)를 면역원으로 사용. 액상형, 0.5 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PPP1R10 (aa 146–195) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605942 |
Product Specific Information
Peptide sequence:
SQSSTQPAEK DKKKRKDEGK SRTTLPERPL TEVKAETRAE EAPEKKREKP
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 79%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
Target Information
RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis.
RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, suggesting that multiple signaling pathways are involved in Pol I transcription.
RPA40 and RPA16 are subunits of Pol I that associate with each other at an early stage of RNA polymerase I assembly.
RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
RPA40, RPA16, and RPA135 encode the three subunits of RNA polymerase I, respectively.
RPA194 is the largest subunit of RNA Pol I and is not a component of Pol II and Pol III.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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