Thermo Fisher Scientific Cortisol Monoclonal Antibody (BGN/C53)
Thermo Fisher Scientific의 Cortisol Monoclonal Antibody (BGN/C53)는 코르티솔 검출용 마우스 IgG3 단클론 항체로, ELISA 등에 적합합니다. 고순도 정제된 액상 형태이며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BGN/C53 |
| Immunogen | Synthetic corticosterone conjugated to BSA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_930206 |
Product Specific Information
Mouse anti-cortisol monoclonal antibody, clone BGN/C53, recognizes cortisol — a glucocorticoid hormone synthesized from cholesterol by the adrenal cortex. It is released in response to pituitary adrenocorticotrophic hormone (ACTH), which is regulated by corticotrophin releasing factor (CRF).
Target Information
Cortisol is the most potent glucocorticoid produced by the human adrenal cortex. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH), regulated by corticotropin releasing factor (CRF).
High cortisol levels inhibit ACTH and CRF secretion via a negative feedback loop. In plasma, most cortisol binds with high affinity to corticosteroid binding globulin (CBG or transcortin).
Cortisol acts through specific intracellular receptors and influences immune function, glucose regulation, vascular tone, and bone metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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