Thermo Fisher Scientific Cortisol Monoclonal Antibody (BGN/C53)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1:500-1:5,000

-

Product Specifications

Species Reactivity

Chemical

Host/Isotype

Mouse / IgG3

Class

Monoclonal

Type

Antibody

Clone

BGN/C53

Immunogen

Synthetic corticosterone conjugated to BSA

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

purified

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_930206

Product Specific Information

Mouse anti cortisol monoclonal antibody, clone BGN/C53 recognizes cortisol, a glucocorticoid hormone synthesized from cholesterol by the adrenal cortex. It is released in response to pituitary adenocorticotrophic hormone (ACTH) which is, in turn, regulated by corticotrophin releasing factor (CRF).

Target Information

Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.