Thermo Fisher Scientific Blood Group A Antigen Monoclonal Antibody (HE-195)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

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View 1 publication 1 publication

Agglutination (AGG)

Assay-dependent

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

HE-195

Immunogen

Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant

Contains

<0.1% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_1070766

Product Specific Information

Human blood group A antigen belongs to a group of carbohydrate determinants carried on both glycolipids and glycoproteins; it is detected on erythrocytes and certain epithelial cells. The antibody HE-195 recognizes human blood group A including weak variants A3 , AX , A3B, AXB. The specifity of antibody HE-195 was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood. Agglutination test A1, A1B, A2B.

Target Information

Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.