Thermo Fisher Scientific FNTA Polyclonal Antibody
Thermo Fisher Scientific의 FNTA 폴리클로날 항체는 인간, 마우스, 랫트 시료에서 FNTA 단백질을 검출합니다. Western blot에 최적화되어 있으며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 제공되며, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FNTA (Accession P49354), corresponding to amino acid residues D52–Y102 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852377 |
Product Specific Information
Antibody detects endogenous levels of total FNTA.
Target Information
FNTA (Farnesyltransferase, CAAX box; alphaCAAX farnesyltransferase alpha subunit, FPTA, FTase-alpha, GGTase-I-alpha, Protein farnesyl transferase/geranyl geranyl transferase type I alpha subunit (PGGT1A), Ras proteins prenyl transferase alpha, Type I protein geranyl-geranyl transferase alpha subunit) is located at locus 8p11 (human).
Prenylation is a common intracellular posttranslational protein modification catalyzed by prenyltransferases. The CAAX farnesyl transferase (EC 2.5.1.21) is an alpha-beta heterodimeric enzyme that catalyzes the attachment of a farnesyl group from farnesyl phosphate to cysteine residues at the fourth position from the C-terminus of proteins ending in the CAAX box. FNTA, the alpha subunit of farnesyl transferase, is shared by geranyl-geranyl protein transferases. It may also regulate intracellular signaling pathways involving p21ras and interact with TGF-beta and activin-type I receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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