
Thermo Fisher Scientific WASF3 Polyclonal Antibody
WASF3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC(P), ICC/IF에 사용 가능. 사람, 마우스, 랫트 반응성. 친화 크로마토그래피로 정제된 액상 항체로, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WASF3 (Accession Q9UPY6), corresponding to amino acid residues P154–E204 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854441 |
Product Specific Information
This antibody detects endogenous levels of total WASF3.
Target Information
WASP (Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 involved in actin polymerization and cytoskeletal organization. The WASP family includes VASP and Mena, which localize at focal adhesions and regulate actin cytoskeleton dynamics. WAVE proteins, related to WASP family members, mediate actin reorganization downstream of Rho family GTPases.
WAVE1 and WAVE2 regulate membrane ruffling by inducing actin filament clusters in response to Rac activation. WAVE proteins promote actin polymerization through cooperation with the Arp2/3 complex. WAVE1 (also known as SCAR) is primarily expressed in the brain, while WAVE2 is broadly expressed, especially in peripheral blood leukocytes. WAVE3 forms a multiprotein complex linking receptor kinases and actin, mediating signals that influence cell shape, motility, and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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