Thermo Fisher Scientific Fumarase Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Fumarase 폴리클로날 항체. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 액상 형태로 4°C 단기, -20°C 장기 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FH. Recombinant protein control fragment (Product #RP-94048). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790055 |
Product Specific Information
Immunogen sequence:
DASVSFTENC VVGIQANTER INKLMNESLM LVTALNPHIG YDKAAKIAKT AHKNGSTLKE TAIELGYLTA EQFDEWVKPK
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (Krebs) cycle, catalyzing the formation of L-malate from fumarate. It exists in both cytosolic and N-terminal extended mitochondrial forms, differing by translation start site. The mitochondrial form loses the extension after import, producing the same cytoplasmic form. This enzyme functions as a homotetramer and is similar to thermostable class II fumarases. Mutations can cause fumarase deficiency and progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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