Thermo Fisher Scientific ORC3 Polyclonal Antibody
ORC3 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체. Western blot 및 파라핀 포매 조직 면역조직화학(IHC)에서 사용 가능. 인간에 반응하며, 서열 상 유사성으로 소, 개, 마우스, 랫에서도 반응 예측. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QKTDHVARLTWGGC) corresponding to the C-terminus amino acids of ORC3L (aa 698–711) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977077 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
Histone deacetylase 2 (HDAC2), also known as transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3).
In humans, HDAC2 is likely involved in regulating chromatin structure during transcription and associates with YY1, a mammalian zinc-finger transcription factor that negatively regulates transcription by tethering RPD3 to DNA as a cofactor.
This regulatory mechanism is highly conserved from yeast to human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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