Thermo Fisher Scientific FLT3 Monoclonal Antibody (66903), PE
인간 FLT3 단백질을 인식하는 Mouse IgG1 단클론 항체로 PE 형광 표지. Flow Cytometry에 적합하며, 565/576 nm에서 최적 발광. 단백질 A/G 정제, 4°C 암소 보관. 연구용으로만 사용 가능.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 66903 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Flt-3/Flk-2 (Asn27–Asn541) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608875 |
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant mouse Flt-3, recombinant human SCF R, PDGF R alpha, or PDGF R beta is observed.
Target Information
FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. Activation occurs via ligand-induced homodimer formation and autophosphorylation, triggering downstream signaling pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells. Mutations causing constitutive activation are associated with acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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