Thermo Fisher Scientific Phospho-CD122 (Tyr364) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Target Information

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and exists in three forms:

• Low affinity form: Monomer of the alpha subunit, not involved in signal transduction
• Intermediate affinity form: Alpha/beta heterodimer
• High affinity form: Alpha/beta/gamma heterotrimer

Both intermediate and high affinity forms participate in receptor-mediated endocytosis and mitogenic signal transduction.
The CD122 gene encodes the beta subunit, a type I membrane protein.
Dysfunction of CD122 is associated with oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.