Thermo Fisher Scientific Phospho-CD122 (Tyr364) Polyclonal Antibody
Rabbit 폴리클로날 항체로, 인산화된 CD122 (Tyr364) 인식. Western blot에 최적화된 검증된 항체. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human IL-2R beta/CD122 around the phosphorylation site of Tyr364 (Q-G-YP-F-F) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555208 |
Target Information
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and exists in three forms:
- Low affinity form: Monomer of the alpha subunit, not involved in signal transduction
- Intermediate affinity form: Alpha/beta heterodimer
- High affinity form: Alpha/beta/gamma heterotrimer
Both intermediate and high affinity forms participate in receptor-mediated endocytosis and mitogenic signal transduction.
The CD122 gene encodes the beta subunit, a type I membrane protein.
Dysfunction of CD122 is associated with oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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