Thermo Fisher Scientific SLC9A7 Polyclonal Antibody
Rabbit polyclonal antibody against human SLC9A7. Validated for ICC/IF applications. Antigen affinity purified and supplied as a liquid in PBS with glycerol. Ideal for research on Na+/H+ exchanger function and intracellular pH regulation.
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- PA567384
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SLC9A7. Recombinant protein control fragment (Product #RP-108044) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664504 |
Product Specific Information
Immunogen sequence:
SWLNIRVGVEE PSEEDQNEHH WQYFRVGVDP DQDPPPNNDS FQVLQGDGPD SARGNRTKQE SAWIFRLWY
Highest antigen sequence identity to orthologs:
- Mouse: 90%
- Rat: 91%
Target Information
Na⁺/H⁺ exchangers (NHE) are plasma membrane intrinsic proteins that mediate exchange of Na⁺ and H⁺ ions across various tissues. NHEs regulate intracellular pH, Na⁺ absorption, cell volume, and may influence cell proliferation. These exchangers are implicated in physiological and pathological states such as hypertension, organ growth, cancer regression, and renal disorders.
At least seven NHE isoforms (NHE1–7) have been cloned, sharing similar primary structures with 10–12 predicted transmembrane domains. NHE7 (human, 725 aa, chromosome Xp11.4) is ubiquitously expressed and predominantly localized to the trans-Golgi network, mediating Na⁺ or K⁺ influx in exchange for H⁺. It shares ~70% homology with NHE6 and ~25% with other NHEs.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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