Thermo Fisher Scientific SYT10 Polyclonal Antibody
Rabbit polyclonal antibody against human SYT10 단백질로, IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Concentration: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SYT10. Recombinant protein control fragment (Product # RP-101200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648156 |
Product Specific Information
Immunogen sequence:
MSFHKEDGVN SLCQKALHIV TELCFAGQVE WEKCSGIFPR DRGSQGGSST DIS
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 83%
Target Information
SYT10 is a Ca²⁺ sensor specifically required for the Ca²⁺-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca²⁺-dependent synaptic vesicle exocytosis. It acts through Ca²⁺ and phospholipid binding to the C2 domain: Ca²⁺ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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