Thermo Fisher Scientific CDH17 Recombinant Rabbit Monoclonal Antibody (ARC1989)
CDH17 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody. Western blot, IHC, ICC/IF, ELISA에 적합. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1989 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human LI Cadherin / Cadherin-17 (Q12864) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898059 |
Product Specific Information
- Positive Samples: HT-29, Mouse large intestine
- Immunogen sequence:
MILQAHLHSL CLLMLYLATG YGQEGKFSGP LKPMTFSIYE GQEPSQIIFQ FKANPPAVTF ELTGETDNIF VIEREGLLYY NRALDRETRS THNLQVAALD
Target Information
CDH17 gene encodes a member of the cadherin superfamily, which includes calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular region with seven cadherin domains and a transmembrane region but lacks the conserved cytoplasmic domain. CDH17 is expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. It may also play a role in the morphological organization of the liver and intestine. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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