Thermo Fisher Scientific NBS1 Polyclonal Antibody
Thermo Fisher Scientific의 NBS1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 WB, IHC, ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제된 Rabbit IgG 폴리클로날 항체로, 세포 손상 복구 및 체크포인트 연구에 적합합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (IHC) | 2.5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 16 amino acid synthetic peptide near the amino terminus of human NIBRIN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Refrigerate at 2–8°C for up to 3 months; for long-term storage, store at −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551737 |
Product Specific Information
- Suggested positive control: rat lung tissue lysate
- PA5-34385 can be used with blocking peptide PEP-1428
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.
This complex is associated with Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity.
It reveals a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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