Thermo Fisher Scientific P2X7 Polyclonal Antibody
P2X7 수용체를 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 IHC(Paraffin/Frozen)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며 연구용으로 사용됩니다.
- 카탈로그번호
- PA528020
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific P2X7 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 103–348 of Human P2X7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545496 |
Product Specific Information
- Predicted reactivity: Mouse (82%), Rat (81%), Dog (91%), Bovine (86%), Guinea pig (83%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The P2X7 gene encodes a purinoceptor for ATP that functions as a ligand-gated ion channel. It mediates ATP-dependent lysis of macrophages through membrane pore formation, allowing passage of large molecules. Activation by ATP in the cytoplasm may link cellular activity to gene expression changes. Multiple alternatively spliced variants exist, most of which meet nonsense-mediated decay criteria.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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