
Thermo Fisher Scientific GSTM3 Polyclonal Antibody
Thermo Fisher Scientific의 GSTM3 Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, WB와 ELISA에 최적화된 다클론 항체입니다. 재조합 GSTM3 단백질(aa 101-225)을 면역원으로 사용하였으며, 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 101–225 of human GSTM3 (NP_0008402) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806377 |
Product Specific Information
- Immunogen sequence: VDIIENQVMD FRTQLIRLCY SSDHEKLKPQ YLEELPGQLK QFSMFLGKFS WFAGEKLTFV DFLTYDILDQ NRIFDPKCLD EFPNLKAFMC RFEALEKIAA YLQSDQFCKM PINNKMAQWG NKPVC
- Positive Samples: HeLa, Mouse liver, Mouse testis
- Cellular Location: Cytoplasm
Target Information
Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme encoded by the GSTM3 gene in humans. It belongs to the mu class of glutathione S-transferases, which play a crucial role in detoxifying electrophilic compounds such as carcinogens, therapeutic drugs, and environmental toxins through conjugation with glutathione.
These genes are located in a cluster on chromosome 1p13.3 and are known to be highly polymorphic, influencing susceptibility to toxins and drug efficacy. Mutations in this gene have been associated with a slight increase in certain cancers due to environmental toxin exposure.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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