Thermo Fisher Scientific GC Vitamin D Binding Protein Monoclonal Antibody (VDBP/4481)
Vitamin D 결합 단백질(GC)에 특이적인 단일클론 항체로 인간 시료에 반응. IHC, Immunoelectrophoresis 등 다양한 응용 가능. 액상 형태, 200 µg/mL 농도, Protein A/G 정제. 4°C 보관, 24개월 안정성 보장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Immunoelectrophoresis (IE)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VDBP/4481 |
| Immunogen | Recombinant fragment (around aa 35–175) of human GC protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is stable for 24 months.
- Positive Control: Human liver, kidney, or pancreas
- Cellular Localization: Secreted
Specificity Comments:
Vitamin D-binding protein (DBP), also known as GC protein, is a multifunctional serum protein that binds to plasma membranes and mediates various cellular functions. The DBP gene is located on human chromosome 4q13.3. DBP transports vitamin D and its metabolites to target organs, has immunomodulatory properties, binds leukocyte surfaces, and interacts with chondroitin sulfate proteoglycan. It enhances C5a chemotactic activity, binds globular actin for clearance from blood, and plays a role in osteoclast differentiation.
Target Information
GC (vitamin D-binding protein) is involved in:
- Vitamin D transport and storage
- Scavenging of extracellular G-actin
- Enhancing C5a chemotactic activity for neutrophils
- Macrophage activation
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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