Thermo Fisher Scientific DCN Polyclonal Antibody, MaxPab
Rabbit polyclonal antibody against human Decorin (DCN). Validated for Western blot applications. Affinity purified and supplied in PBS buffer without preservative. Suitable for research use in cartilage matrix and collagen interaction studies.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DCN (NP_001911.1, 1–359 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MKATIILLLL AQVSWAGPFQ QRGLFDFMLE DEASGIGPEV PDDRDFEPSL GPVCPFRCQC HLRVVQCSDL
GLDKVPKDLP PDTTLLDLQN NKITEIKDGD FKNLKNLHAL ILVNNKISKV SPGAFTPLVK LERLYLSKNQ
LKELPEKMPK TLQELRAHEN EITKVRKVTF NGLNQMIVIE LGTNPLKSSG IENGAFQGMK KLSYIRIADT
NITSIPQGLP PSLTELHLDG NKISRVDAAS LKGLNNLAKL GLSFNSISAV DNGSLANTPH LRELHLDNNK
LTRVPGGLAE HKYIQVVYLH NNNISVVGSS DFCPPGHNTK KASYSGVSLF SNPVQYWEIQ PSTFRCVYVR
SAIQLGNYKTarget Information
Decorin is a member of the small leucine-rich proteoglycan (SLRP) family, along with biglycan. It is found in the interterritorial region of cartilage and interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. Decorin interacts with fibronectin, thrombospondin, C1q, EGFR, and TGF-β, and may play a role in the cell cycle of chondrocytes. The decorin neoepitope fragment (sequence PKTLQE) is generated by MMP-3 or ADAMTS-4 cleavage at Glu154–Leu155 of the decorin core protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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