Thermo Fisher Scientific DCK Monoclonal Antibody (1G6)
인간 DCK 단백질을 인식하는 mouse monoclonal antibody. ELISA에 적합하며, 항바이러스 및 항암제 내성 연구에 유용. 비결합형 액상 형태로 제공되며, PBS(pH 7.4) buffer에 보존제 없음. -20°C에서 보관 권장.
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Applications
- ELISA (ELISA)
Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G6 |
| Immunogen | DCK (NP_000779, 161 a.a. ~ 260 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
WMNNQFGQSL ELDGIIYLQA TPETCLHRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTNFDYLQE VPILTLDVNE DFKDKYESLV EKVKEFLSTL
Target Information
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased DCK activity is linked to enhanced activation of these compounds into cytotoxic nucleoside triphosphate derivatives. DCK is clinically significant due to its role in drug resistance and sensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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