Thermo Fisher Scientific EPC1 Monoclonal Antibody (4F7)

Applications

Tested Dilution

Publications

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

4F7

Immunogen

EPC1 (NP_079485, 695 a.a. approximately 798 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EPC1,uniProtId:Q9H2F5-1,ncbiNodeId:9606,antigenRange:695-798,antigenLength:836,antigenImageFileName:H00080314-M01A_EPC1_Q9H2F5-1_House_mouse.svg,antigenImageFileNamePDP:H00080314-M01A_EPC1_Q9H2F5-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: KGLHLSSTTP TALVHTSPST AGSALLQPSN ITQTSSSHSA LSHQVTAANS ATTQVLIGNN IRLTVPSSVA TVNSIAPINA RHIPRTLSAV PSSALKLAAA ANCQ

Target Information

EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.