Thermo Fisher Scientific PRAME nuclear receptor transcriptional regulator Monoclonal Antibody (PRAME/9189)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

PRAME/9189

Immunogen

Recombinant fragment (around aa100-250) of human PRAME protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRAME,uniProtId:P78395-1,ncbiNodeId:9606,antigenRange:100-250,antigenLength:509,antigenImageFileName:23532-MSM9-P1ABX_PRAME_P78395-1_House_mouse.svg,antigenImageFileNamePDP:23532-MSM9-P1ABX_PRAME_P78395-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Dry ice (international)

Product Specific Information

Positive Control:Human testis or melanoma.

Cellular Location: Nucleus. Chromosome. Cytoplasm. Golgi apparatus. Cell membrane

Target Information

This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.