Thermo Fisher Scientific PRAME nuclear receptor transcriptional regulator Monoclonal Antibody (PRAME/9189)
인간 PRAME 단백질을 표적으로 하는 단클론 항체로 면역조직화학(IHC)에 적합합니다. Human 시료 반응성이 있으며, Mouse IgG2b, kappa 아이소타입입니다. 핵, 세포질, 골지체 등 다양한 세포 위치에서 PRAME 발현 검출에 활용됩니다.
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Thermo Fisher Scientific PRAME Nuclear Receptor Transcriptional Regulator Monoclonal Antibody (PRAME/9189)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PRAME/9189 |
| Immunogen | Recombinant fragment (around aa100–250) of human PRAME protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Dry ice (international) |
Product Specific Information
- Positive Control: Human testis or melanoma
- Cellular Location: Nucleus, Chromosome, Cytoplasm, Golgi apparatus, Cell membrane
Target Information
This gene encodes an antigen predominantly expressed in human melanomas and recognized by cytolytic T lymphocytes. It is not expressed in normal tissues except testis. This expression pattern is similar to other CT antigens such as MAGE, BAGE, and GAGE. However, unlike these antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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