Thermo Fisher Scientific TNFRSF13B Monoclonal Antibody (4G4)
Human TNFRSF13B 단백질을 인식하는 Mouse monoclonal antibody (Clone 4G4). Western blot 및 ELISA에 사용 가능하며, PBS buffer에 보존된 액상 형태. 면역반응 및 B세포 활성 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G4 |
| Immunogen | TNFRSF13B (NP_036584.1, 2 a.a. ~165 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQVA LVYS
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. Two novel members, BAFF (BLyS/TALL-1/THANK/zTNF4) and APRIL (TALL-2), have been identified.
- BAFF: Acts as a B cell activator, inducing proliferation and immunoglobulin secretion.
- APRIL: Regulates both immunological and non-immunological cell growth.
- Receptors: BCMA, TACI, and BAFF-R bind to BAFF and APRIL.
- TACI function: Regulates humoral immune responses, activates NF-kappa-B and c-jun N-terminal kinase, and is involved in B cell–associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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