Thermo Fisher Scientific TNFRSF13B Monoclonal Antibody (3E3)
TNFRSF13B 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 ELISA에 최적화됨. 인간 시료에 반응하며, PBS(pH 7.4) 저장용액에 보존제 없이 공급. 면역반응 및 세포사멸 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E3 |
| Immunogen | TNFRSF13B (NP_036584.1, 2–165 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQVA LVYS
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. Two novel members, BAFF (BLyS/TALL-1/THANK/zTNF4) and APRIL (TALL-2), were identified.
- BAFF: Acts as a B cell activator, inducing proliferation and immunoglobulin secretion.
- APRIL: Regulates both immunological and non-immunological cell growth.
Three receptors—BCMA, TACI, and BAFF-R—bind BAFF and APRIL.
TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-Jun N-terminal kinase, and are involved in B cell–associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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