Thermo Fisher Scientific TDP1 Monoclonal Antibody (OTI4H1), TrueMAB
Human TDP1 단백질을 인식하는 Mouse monoclonal antibody (OTI4H1). Western blot에 최적화되어 있으며, 고순도 Affinity chromatography 정제. PBS/BSA/glycerol buffer로 안정화되어 장기 보관 가능.
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Applications
- Western Blot (WB)
Tested dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H1 |
| Immunogen | Full length human recombinant protein of human TDP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.78 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA.
It may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks.
This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains.
Mutations in this gene are associated with spinocerebellar ataxia with axonal neuropathy (SCAN1).
Several transcript variants may exist, with two major variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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