Thermo Fisher Scientific Tapasin Polyclonal Antibody
Tapasin 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, IHC, ICC/IF에 사용 가능. 인간 및 랫트 반응성. Affinity chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TAPBP (Accession O15533), corresponding to amino acid residues P111–V161 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851937 |
Product Specific Information
This antibody detects endogenous levels of total TAPBP.
Target Information
The TAPBP gene encodes a transmembrane glycoprotein that mediates the interaction between newly assembled MHC class I molecules and the transporter associated with antigen processing (TAP). This interaction is essential for optimal peptide loading on MHC class I molecules. Up to four complexes of MHC class I and TAPBP may bind to a single TAP molecule. The protein contains a C-terminal double-lysine motif (KKKAE) that retains membrane proteins in the endoplasmic reticulum. The gene is located within the major histocompatibility complex on chromosome 6, and alternative splicing results in three transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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