Thermo Fisher Scientific IL17RE Polyclonal Antibody
IL17RE 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·생쥐·랫트 반응성이 있음. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 2–8°C 보관, 장기 보관 시 -20°C. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the center of human IL-17RE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551851 |
Product Specific Information
- A suggested positive control is human ovary tissue lysate.
- PA5-34499 can be used with blocking peptide PEP-1542.
Target Information
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that, with IL-17A, plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens.
IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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