Thermo Fisher Scientific IL6 Monoclonal Antibody (3E8)
Thermo Fisher Scientific의 IL6 Monoclonal Antibody (3E8)는 인간 IL-6 단백질을 표적으로 하는 Mouse IgG2a 형 단일클론 항체입니다. Western blot과 ELISA에 사용 가능하며, 염증 및 면역반응 연구에 적합합니다. 액상 형태로 제공되며 PBS buffer에 보관됩니다.
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Applications
- Western Blot (WB): 1–5 µg/mL
- ELISA: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E8 |
| Immunogen | IL6 (NP_000591, 29–212 a.a.) full-length recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Target Information
IL-6 is a cytokine involved in inflammation and B cell maturation. It acts as an endogenous pyrogen and is secreted at sites of acute and chronic inflammation, inducing transcriptional inflammatory responses via the IL-6 receptor alpha.
This gene is associated with various inflammation-related diseases such as diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi Sarcoma, and Rheumatoid Arthritis. Elevated IL-6 levels have also been observed in viral infections, including COVID-19 (SARS-CoV-2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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