Thermo Fisher Scientific NR0B2 Monoclonal Antibody (OTI5F10), TrueMAB
NR0B2 단백질을 표적하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 사용 가능. 고순도 친화 크로마토그래피 정제, 무보존제 PBS 버퍼에 동결건조 형태. 휴먼 NR0B2 풀랭스 단백질을 항원으로 제작된 TrueMAB 형 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F10 |
| Immunogen | Full length human recombinant NR0B2 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The NR0B2 protein is an orphan nuclear receptor that lacks a conventional DNA-binding domain but includes a ligand-binding domain. It interacts with retinoid, thyroid, and estrogen receptors, inhibiting their ligand-dependent transcriptional activation. This protein represses nuclear hormone receptor-mediated transactivation through competition with coactivators and direct transcriptional repression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: CF806319_NR0B2_Q15466-1_House_mouse.svg, CF806319_NR0B2_Q15466-1_House_mouse_PDP.jpeg)
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