Thermo Fisher Scientific NR0B2 Monoclonal Antibody (OTI6D8), TrueMAB
NR0B2 단백질을 인식하는 Mouse monoclonal antibody(OTI6D8)로 Western blot에 적합. Human 반응성. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer에 보존. 연구용으로 핵수용체 관련 전사조절 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D8 |
| Immunogen | Full length human recombinant protein of human NR0B2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The NR0B2 gene encodes an orphan nuclear receptor lacking a conventional DNA-binding domain but containing a ligand-binding domain. It belongs to the nuclear hormone receptor family, which includes transcription factors regulated by small hydrophobic hormones. NR0B2 interacts with retinoid, thyroid, and estrogen receptors, inhibiting their ligand-dependent transcriptional activation. It represses nuclear hormone receptor-mediated transactivation through competition with coactivators and its intrinsic repressor function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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