Thermo Fisher Scientific SMAD5 Recombinant Rabbit Monoclonal Antibody (5W8T5)
SMAD5 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포 발현 시스템에서 생산되었으며, Protein A로 정제된 액상 형태입니다. 인간 및 랫트 시료에 반응하며, 안정적인 저장용 PBS 버퍼 포함.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5W8T5 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 186–260 of human Smad5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
PLSPNSPYPP SPASSTYPNS PASSGPGSPF QLPADTPPPA YMPPDDQMGQ DNSQPMDTSN NMIPQIMPSI SSRDV
Target Information
SMADs are members of the MAD-related family of molecules. These intracellular proteins are essential components in the signaling pathways of serine/threonine kinase receptors belonging to the transforming growth factor beta (TGF-β) superfamily.
SMADs are categorized as:
- Receptor-regulated SMADs (R-SMADs): SMAD1, 2, 5, 8, 9
- Common-mediator SMAD (co-SMAD): SMAD4
- Inhibitory SMADs (I-SMADs): SMAD6, 7
SMAD1, 5, 8, and 9 share high sequence homology, and antibodies may recognize common epitopes among them. SMAD8 and SMAD9 are often used interchangeably in literature.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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