Thermo Fisher Scientific LRP12 Isoform A Precursor Polyclonal Antibody
Human LRP12 Isoform A Precursor를 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합. 고순도 Affinity chromatography로 정제된 액상 항체. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LRP12 (Accession Q9Y561), corresponding to amino acid residues T408–C458 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853736 |
Product Specific Information
Antibody detects endogenous levels of total LRP12.
Target Information
Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (GP330), VLDLR (very low density lipoprotein receptor), and ApoER2 are characterized by cysteine-rich class A repeats, EGF-like repeats, YWTD repeats, and O-linked sugar domains.
LRP12 (also designated ST7) is a member of this family involved in internalization of lipophilic molecules and/or signal transduction. It interacts with RACK1, MADHIP, and Integrin beta-1-binding protein 3, and is expressed in heart, skeletal muscle, brain, lung, placenta, and pancreas. Overexpression of LRP12 may be associated with oral tumors, suggesting its potential role as an oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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