Thermo Fisher Scientific AMID Polyclonal Antibody
Rabbit Polyclonal AMID 항체로, Human 시료에 반응하며 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었고, PBS buffer(40% glycerol, 0.02% sodium azide)로 보관됩니다. 단기 4°C, 장기 -20°C 저장 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human AMID. Recombinant protein control fragment (Product # RP-105802) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856379 |
Product Specific Information
Immunogen sequence:
MLVDMKDSFH HNVAALRASV ETGFAKKTFI SYSVTFKDNF RQGLVVGIDL KNQMVLLQGG EALPFSHLIL ATGSTGPFPG KFNEVSSQQA AIQAYEDMVR QVQRSRFIVV VGGGSAGVEM AAEIKTEYPE KEVTLIHSQV ALAD
Target Information
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3) is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor (AIF). Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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