Thermo Fisher Scientific Par4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms.

• Intracellular mechanism: Inhibition of pro-survival pathways and activation of Fas-mediated apoptosis.
• Extracellular mechanism: Binding of secreted form to GRP78 on the cell surface, activating the extrinsic apoptotic pathway.
  This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated in different tumors.
  The encoded protein also plays an important role in the progression of age-related diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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