Thermo Fisher Scientific Human PDGFRA (PDGFR alpha), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
• For larger sizes, reduce freeze/thaw cycles by preparing aliquots (minimum 20 µL).
• Do not store kinase diluted.
• Properly stored at -80°C, guaranteed for 6 months from date of purchase.
• Protein Form: Cytoplasmic

Target Information

PDGFRA is a cell surface receptor tyrosine kinase that binds members of the platelet-derived growth factor family. These growth factors act as mitogens for mesenchymal-origin cells. The bound growth factor determines whether the receptor forms a homodimer or heterodimer with PDGFR beta. Knockout mouse studies show that homozygosity is lethal, and the alpha form of PDGFR plays a critical role in kidney development, as heterozygous mice exhibit defective kidney phenotypes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.